The eplex RP2 Control M451 is intended for use as an external positive and negative quality control to monitor the performance of in vitro laboratory nucleic acid testing procedures for the qualitative detection of pathogens on the eplex respiratory pathogen (RP2) panel 2 performed on the eplex System (GenMark Diagnostics, Inc.). eplex RP2 Control M451 is composed of 3 controls, eplex RP2 Positive A, eplex RP2 Positive B and eplex RP2 Negative. eplex RP2 Control M451 is comprised of 12 tubes, 4 tubes of each positive control, A and B, and 4 tubes of negative control, 200 μL each. The eplex RP2 Positive controls are composed of synthetic DNA and RNA suspended in a non-infectious solution of buffers, preservatives and stabilizers. The eplex RP2 Negative control contains buffer and preservatives.